ABSTRACT

Ulcers result when there is loss of all of the epidermis and at least a portion of the dermis. There are many causes of ulcers. Leg ulcers are frequently caused by chronic venous insufficiency, arterial disease, neuropathy, or a combination of factors (1). Ulcers are less commonly caused by infections. A diversity of infections may cause ulcers, and diagnosis is usually difficult without a culture or biopsy. The differential diagnosis of infectious ulcers includes bacterial, fungal, parasite, and viral etiologies (Table 1). Infectious Etiology of Leg Ulcers

Bacterial

Ecthyma

Ecthyma gangrenosum

Necrotizing fasciitis

Mycobacterial

Anthrax

Spirochetal

Fungal

Mycetoma

Sporotrichosis

Chromoblastomycosis

Blastomycosis

Histoplasmosis

Lobomycosis

Parasite

Leishmaniasis

Amebiasis

Viral

Herpes simplex

Cytomegalovirus