ABSTRACT
This chapter is meant to be a basic guide for nontoxicologists or nonexperts in
developmental and reproductive toxicology (DART) who are responsible for contracting
chemical safety studies to outside laboratories and need help in understanding the subject
enough to be able to use the appropriate terminology, review protocols, interpret study
results, and understand the implications of specific findings to risk assessment. It is not
the purpose of this review to discuss specific methodology or specific agents and their
mechanisms of toxicity. If the reader is interested, the following books are excellent
sources for further inquiries into this area of toxicology (1-5).