ABSTRACT
INTRODUCTION In his 1817 An Essay on the Shaking Palsy, Parkinson (1) recorded many features of the condition that now bears his name. Parkinson emphasized tremor at rest, fl exed posture, festinating gait (Fig. 4.1), dysarthria, dysphagia, and constipation. Charcot and others later pointed out that the term paralysis agitans used by Parkinson was inappropriate, because in Parkinson’s disease (PD), strength was usually well preserved and many patients did not shake.
