ABSTRACT
Disordered sleep shows a high prevalence with between 10-50% of the general population reporting difficulty sleeping, depending on the methods used to assess insomnia and the population studied (1,2). In addition, sleep disturbance and loss of sleep occur in association with many psychiatric disorders as well as multiple medical conditions including cardiovascular, infectious, and inflammatory diseases (3-5). Epidemiological data increasingly implicate sleep loss as a predictor of cardiovascular and noncardiovascular disease mortality (3,6), and sleep loss is thought to adversely affect resistance to infectious disease, increase cancer risk, and alter inflammatory disease progression.
