ABSTRACT

Figure 11.1 Schematic of the biosensor used to measure variations of the optical index around that of water n5, as a function of biomaterials concentration. The index of the glass prism is n1. The index of the gold layer n3, as well as that of the chromium layer, is complex and depends on the incoming wavelength l0, which will be fixed in this study, as well as that of the chromium layer, n2 (l0). The functionalization layer is used to fasten the biological molecules of interest in the vicinity of the gold layer. Its optical index is n4. The thicknesses of the layers are e1, e2, and e3 for the chromium, the gold, and the functionalization layer, respectively. The angle of incidence of the illumination is q.