ABSTRACT

Many years later it would be shown that the effect of the ovarian wedge resection was to reduce the intraovarian testosterone level6. Resumption of menses was an unexpected finding following the surgery. Stein and Leventhal4 then described a subgroup of patients with polycystic ovarian syndrome (PCOS) with symptoms of obesity, amenorrhea, hirsutism, the inability to conceive with bilateral ovarian engorgement as having Stein-Leventhal syndrome. Followup studies reported a reversal of amenorrhea to cyclic menses in 95% of patients and conception

in 85% of patients in those treated with ovarian wedge resection7.