ABSTRACT

The experience in handling immature oocytes has been obtained from two main groups. The first group is women suffering from polycystic ovarian syndrome (PCOS), as these women are extremely sensitive to stimulation with follicle stimulating hormone (FSH) in assisted reproduction, and they have a significant risk of developing ovarian hyperstimulation syndrome (OHSS). The second group is regularly cycling women with normal ovaries referred for in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In both groups aspiration of immature oocytes has been performed in unstimulated cycles and after priming with FSH, and/or after priming with human chorionic gonadotropin (hCG) before aspiration. In this chapter the experience obtained after handling immature oocytes after FSH priming is summarized.