ABSTRACT
The challenge with IVM is to retrieve immature oocytes before ovulation, usually in mid to late follicular phase, and then return a cleaving embryo a few days later into the uterus. The use of minimal FSH stimulation during the early follicular phase could potentially increase the endometrial thickness before IOC and thus improve the outcome. However, there does not seem to be any benefit of early follicular phase FSH priming in women with regular cycles and normal ovaries35. On the other hand, in PCOS patients with no spontaneous follicle development and subsequent endometrial proliferation, there were more pregnancies in the FSH primed group compared to the non-primed group, albeit no difference in the endometrial thickness at IOC between the groups was observed36. Others have not found any beneficial effect of FSH priming in PCOS patients32,37.
