ABSTRACT
In this chapter we describe and discuss the International AIDS
Vaccine Initiative (IAVI) as a case study for understanding the
emerging role of health product development partnerships (PDPs)
in providing new solutions to health problems in low-resource
settings. Based on a broader analysis of the emergence and impact
of global health partnerships, this chapter highlights the need
for multidisciplinary and multi-institutional approaches, which are
exemplified by IAVI and similar PDPs, and considers the extent
to which these translational approaches are leading the way in
terms of developing new vaccines for HIV/AIDS and other neglected
diseases. The contextual historical, organizational, and scientific
issues surrounding these efforts are presented and discussed in
this chapter, leading to our conclusion that PDPs such as the IAVI
are playing increasingly crucial roles in translational medicine (TM)
within developing countries.
