ABSTRACT
Quantitative MRI techniques have become an important tool in neurobiology and clinical neuroscience. Today, broad availability of modern MRI scanners and the maturity of MRI protocols offer easy access to high-resolution structural scans of the human head and brain. Acquired datasets are a valuable resource to address important questions in basic and clinical research. Anatomical imaging provides a “snapshot” of the macroscopic brain morphology. Example applications are as follows:
1. The brain compartments and substructures can be quantified and characterized in terms of their volume, shape, and textural properties. Resulting numbers may be included in statistical models and related to demographic, genetic, metabolic, or clinical data of single subjects or groups.
