ABSTRACT

Uveal melanocytes are embryonically derived from nonpigmented precursor cells, melanoblasts, which originate from neural crest cells that migrate to the uveal tract. Uveal melanocytes are well established in the uveal tract at birth, dispersed throughout the stroma. In the iris, uveal melanocytes are present throughout the stroma and form a dense layer at the anterior surface of the iris just under a layer of fibroblasts. In the ciliary body, uveal melanocytes can be less dendritic (at the base) or dendritic (in the ciliary processes). In the choroid, uveal melanocytes are present in the stroma, especially gathered around the blood vessels. A large number of uveal melanocytes appear in the suprachoroidal lamellae [1].