ABSTRACT

INTRODUCTION Pregnancy is associated with hormonal changes which cause variable responses within the neuropeptide system and receptor status within the brain including striatal areas. A natural consequence of this is the occurrence of movement disorders more frequently or only during pregnancy. These conditions include restless legs syndrome and chorea, among other rarer disorders. The pathophysiology is complex and mostly unclear. The following sections discuss conditions that may arise de novo in pregnancy and those that may be present in women of childbearing age.