ABSTRACT
This chapter describes the major immune-mediated renal and reproductive diseases of dogs and cats. The best defined example of the former is immune complex glomerulonephritis (ICGN), which is a relatively common and clinically significant disease of the dog and cat. In contrast, true autoimmune glomerulonephropathy is rarely documented, and the role of the immune system in other diseases such as chronic interstitial nephritis is poorly characterized. Reproductive immunology of the dog and cat is also an area about which relatively little is known compared with other species. Of greatest clinical relevance is the fact that a proportion of cases of infertility in male dogs may have an immune-mediated pathogenesis.
