ABSTRACT
The surgical management of CC patients should be tailored on the basis of prognostic factors. In particular, the surgeon should perform a less radical operation taking into account the tumor size, the nodal spread, and the parametrial involvement, which are considered the most important factors linked to prognosis (8,9). A study reports that pretreatment evaluation of these adverse prognostic factors in patients affected by International Federation of Gynecology and Obstetrics (FIGO) stages IA2-IB1 CC is feasible, with the intent to determine if a less radical surgery is applicable and safe (10). Factors reported to be associated with a low risk of parametrial disease include tumor occupying less than a half of the cervical volume (11), tumor <2 cm (12), and tumor <2 cm with no lymphovascular space invasion (LVSI) (13). The rate of parametrial invasion in early CC with diameter <20 mm, depth of stromal invasion <10 mm, and negative pelvic lymph nodes is very low (14).
