ABSTRACT

This chapter introduces a new point-of-care testing (POCT) platform for the detection of avian influenza (AI) with a nanogap-embedded separated double-gate FET (DGFET) array and a general-purpose readout platform. The nanogap-DGFET was fabricated using the standard microfabrication technologies used for complementary metal–oxide–semiconductor (CMOS) transistors. However, nanogap-DGFET devices are insensitive to the Debye length because the measurement occurs in a dry state. This Debye-screening-free feature arises from the working principle of the nanogap-DGFET, which is based on permittivity changes. Along with the development of medical technologies, consumers are paying more attention to personal health monitoring systems that use biosensors to provide accurate, easy and inexpensive medical checkups and diagnostics to identify many diseases in their early stages.