ABSTRACT
For many problems in bioelectric theory, investigators analyze the transmembrane and interstitial potential distributions that arise from models that include prescribed tissue conductivities and ionic currents owing through membrane channels. This chapter examines the likely values for interstitial and intracellular microimpedances as derived from the available data for tissue and cellular electrical properties in the ventricular myocardium. It considers the impact a rapid and routine measurement strategy would have on an improved understanding of arrhythmia substrate development. Finally, the chapter presents an initial progress achieved toward interstitial and intracellular microimpedances as a standard component of electrophysiological studies, assuming that closely spaced electrodes are available for stimulation and recording.
