ABSTRACT
Transcranial magnetic stimulation (TMS) is a noninvasive technique used to apply brief magnetic pulses to the brain. Pulses are administered by passing high currents through an electromagnetic coil placed upon the scalp that can induce electrical currents in the underlying cortical tissue, thereby producing a localized axonal depolarization. TMS coil may be designed in such a conguration that the various elements are scattered around the desired region or path, so that passing a current in each element will produce a signicant eld at the desired deep brain region. TMS coil may be designed in such a conguration that the various elements are scattered around the desired region or path, so that passing a current in each element will produce a signicant eld at the desired deep brain region. TMS of Deep Prefrontal Regions e medial prefrontal and orbitofrontal regions are known to be associated with reward circuits.
