ABSTRACT

Diffusion magnetic resonance imaging (dMRI) is a powerful imaging protocol that allows for the assessment of the organization and integrity of fibrous tissue. The imaging works by measuring the diffusion of water molecules within the body. This diffusion is restricted by cell membranes and as such, rates of diffusion are far less in directions perpendicular to fibrous tissue than parallel to the fibers. With enough diffusion measurements along different directions in 3D, we can noninvasively obtain a profile of the diffusion at various points within the imaged subject.