ABSTRACT

With the advent of different medical imaging modalities, clinicians can now perform diagnosis in a minimally invasive manner. Nevertheless, each modality currently only provides particular types of information. CT and MRI, for 620example, provide structural information of our body (e.g., an anatomical map), but do not convey functional information * (i.e., relating to metabolic functions of an imaged organ). Conversely, modalities such as PET and SPECT capture functional but not structural information. This motivates image registration, the task of bringing two medical images into spatial alignment. Once images are aligned, information from different modalities can then be integrated and examined as a whole.