ABSTRACT

Ultraviolet radiation (UVR) penetrates the human skin at different shallow depths depending on the wavelength and is absorbed by a number of biomolecules. UVR exerts a variety of biological effects, some of which are of therapeutic relevance in the management of skin diseases. In particular, ultraviolet (UV) phototherapies exert an immunomodulatory effect through altered expression of cell surface-associated molecules, production of soluble mediators, and induction of apoptosis in pathogenic cells.