ABSTRACT

The role of the bioreceptor is typically to convert or accelerate the conversion of the analyte of interest into another chemical species and/or physical property that can be sensed and then transformed into an electrical signal by the transducer. The transducer could be an electrode such as a pH or dissolved oxygen probe. In an ideal situation, where the sample matrix is not too complex, the detection of an analyte with this device would be accomplished without pretreatment or the addition of any reagent. However, the lifetime, stability, reproducibility, and calibration requirements of the biosensor are inuenced signicantly by the chosen bioreceptors.