ABSTRACT
A biocompatible surface is important, not only for blood-contacting medical devices, but also for subcutaneously implanted diagnostic devices. Hemodialysis is one of the most important methods for blood purification [1]. The properties required for a hemodialysis membrane are an excellent ultrafiltration rate, permeability by solutes, mechanical strength, and blood compatibility. Many synthetic polymer membranes have been investigated to raise the efficiency of dialysis; however, cellulose membranes are still used worldwide for 50% of hemodialysis. Although the cellulose membrane has both good permeability and mechanical strength, its blood compatibility must be further improved for better hemodialysis [2]. Thus, it is necessary to infuse an anticoagulant such as heparin
during hemodialysis to prevent coagulation. Moreover, the cellulose membrane induces significant activation of the complement system due to strong interactions between the membrane surface and complement proteins [3].
