ABSTRACT

Erythrodermic skin can develop a shiny look as a result of epidermal thinning. Erythrodermic cutaneous T-cell lymphoma (CTCL) and erythroderma associated with an underlying malignancy are often persistent and refractory to treatment. Exfoliative erythroderma starts with erythematous patches that become confluent, covering the greater part of the cutaneous surface. Erythroderma has been reported in patients with HIV infection in various populations. Some reports in the literature suggest that erythroderma in young people is most commonly caused by seborrheic dermatitis and genodermatoses. A variety of cutaneous and systemic diseases can manifest as exfoliative erythroderma. In various series and case reports erythroderma has been reported in association with malignancies other than CTCL. Successful treatment of recalcitrant, erythroderma-associated pruritus with etanercept has been reported. Drug-induced erythroderma usually appears suddenly and clears rapidly with discontinuation of the causative drug.