ABSTRACT
ABSTRACT Lymphoma is a type of hematological cancer which occurs in the immune system, and specically starts in lymphocytes. Lymphoma is basically of two types: Hodgkin’s and non-Hodgkin’s lymphoma (NHL). This chapter will specically focus on Hodgkin’s lymphoma (HL), whose subtypes are nodular lymphocyte-predominant Hodgkin’s lymphoma (NLPHL) and classical Hodgkin’s lymphoma (cHL). The characteristic cell types involved in these subtypes are different from each other. Biomarkers are another critical factor in making the correct identication of each subtype. Biomarkers can be categorized into different groups such as origin-related, chromosomal, cytokine, chemokine, and some important pathways-related markers. These biomarkers are not only important to distinguish subtypes but also critical to determine further treatment strategies for disease. Due to the importance of biomarker knowledge, we have reviewed signicant HL biomarkers in this chapter.
