ABSTRACT

Retinal vessel segmentation and the quantification of morphological attributes of retinal blood vessels, such as length, width, tortuosity and branching pattern, and angles are utilized for diagnosis, screening, treatment, and evaluation of various cardiovascular [1] and ophthalmologic diseases [2] such as hypertension, arteriosclerosis, chorodial neovascularization, and diabetes [3]. Automatic detection and analysis of the vasculature can assist in the implementation of screening programs for diabetic retinopathy [4], evaluation of retinopathy of prematurity [5], arteriolar narrowing [6], the relationship between vessel tortuosity and hypertensive retinopathy [7], vessel diameter measurement in relation to

CONTENTS

3.1 Introduction ..........................................................................................................................23 3.1.1 Ensemble Classification ..........................................................................................25