DOI link for Liver Transplantation
Liver Transplantation book
An improvement in surgical techniques and medical management along with advances in immune suppression has facilitated our advancement in liver transplant medicine. Liver transplantation is performed in over 100 centers around the world. Indication for transplantation may be either disease-related or function-related. In children with Alagille syndrome, for example, liver transplantation may be indicated to address severe intractable pruritis secondary to bile acid deposition despite normal hepatic synthetic function. Living-related donor transplantation is a procedure in which a healthy living person donates part of their own liver to a related recipient. In most cases of a whole liver transplantation, several anastomotic connections are made. Biliary strictures are fairly common in pediatric liver transplant patients, occurring in up to 35% of patients in some studies. Early post-transplant infections can have a devastating consequence on graft survival and overall patient care. In general, 37–47% of catch-up growth occurs after 6 months post-transplantation.