ABSTRACT
One of the major challenges in chemical analysis is how to deal with the lack of selectivity that is typical of chemical sensors. This chapter discusses the main aspects underlying the application of Blind Source Separation (BSS) methods to the problem of quantitative analysis via Smart chemical sensor arrays. It provides a brief introduction to potentiometric sensors and introduces the BSS problem. It also provides an overview on the existing results concerning the application of BSS methods to quantitative analysis via potentiometric sensor arrays. It focuses on the discussion of some important practical aspects related to the use of BSS methods to performing chemical analyses. The application of BSS methods to chemical sensor arrays is a relative new topic. The chapter aims to provide an overview on the application of BSS methods to potentiometric sensor arrays. The results are promising, since these methods may work even if only a reduced number of calibration points are available.
