ABSTRACT
Biosensors based on carbon nanomaterials have been drawing attention due to their enhanced electrical conductivity, better stability, excellent structural and catalytic properties, and high loading of biocatalysts. Carbon nanofibers (CNFs) have excellent conductive and structural properties when compared with nanotubes, which make them excellent candidates as electrodes as well as immobilizing substrates. If realized on a silicon-compatible platform, they can be easily integrated with existing sensor technologies for the development of a fully integrated bioChem lab-on-a-chip. Carbon electrodes have been proven to be an excellent choice for enzymatic amperometric biosensors in terms of the range of functionality and the cost-effectiveness. Potentially, CNF-based biosensors have extensive applications such as glucose detection, alcohol detection, nicotinamide adenine, dinucleotide detection and K562 cell detection. Successful commercial realization of the CNF biosensors will require further research to overcome number of challenges associated with the material properties, growth technologies, functionalization of the target biomolecules, and packaging strategies.
