ABSTRACT

Normal visual function requires the shape of the globe to remain fixed and the optical pathway from the cornea to the retina to remain clear. The anterior portions of the larger processes have many capillary fenestrations and epithelial mitochondria, indicating specialization for aqueous humor production. The posterior chamber aqueous humor is modified by diffusion of molecules into or out of the surrounding tissue. The rate at which aqueous humor enters the anterior chamber in the normal human eye averages about ±2.5 ml/min. In the primate trabecular outflow pathway, the aqueous humor drains sequentially through the trabecular meshwork, Schlemm’s canal, collector channels, episcleral veins, and anterior ciliary veins and into the systemic circulation. The intraocular pressure (IOP) declines over the time interval, and with the aid of the Friedenwald tables, the change in the IOP allows one to infer the volume of aqueous humor displaced from the eye.