ABSTRACT

ABSTRACT: This study evaluates the efficiency of intraoperative botulinum toxin A (BTA) injection as an adjunct to the surgical treatment of large-angle esotropia or exotropia. Ten patients were included in the study. Mean age of the patients was 27 20. Seven patients had esotropia and 3 patients had exotropia, with a deviation greater than 60 prism diopters (PD). Five units of BTA was injected into one of the recessed horizontal rectus muscles in all of the patients intraoperatively. The average follow-up was 14 10 months. The average final deviations in the esotropia and exotropia groups were 13 9.6 PD and 4.7 5 PD respectively. The final deviation was within 10 PD in 70% of the patients. Our results suggest that combined use of BTA and surgery may prove useful to reduce the number of muscles to be operated on in large angle deviations.

1 INTRODUCTION