ABSTRACT
ABSTRACT: Objective: To demonstrate metabolic changes happening in brain cortex in strabismus. Methods: Single photon emission computed tomography (SPECT) of brain was made in congenital esotropia, previous and after treatment. Results: Case 1: SPECT showed hypo-perfusion in left frontal lobe (7.38). Strabismus was corrected with botulinum toxin obtaining binocularity. Control SPECT showed correction of lobe (1.19). Case 2: had hypoactivity in left parietal area (8.59), strabismus was corrected with botulinum and binocularity was demonstrated, control SPECT showed increase of hypoactivity levels (5.95). Case 3: strabismus was corrected under surgery obtaining binocularity. SPECT had hypoactivity in right hemisphere (3, 4, 5 areas 0.7, 3.71, 11.09), positive changes after treatment was demonstrated (9.78, 6.44, 3.22). Conclusions: Metabolic changes in brain happened in congenital esotropia. In all cases Brain SPECT could demonstrate improvement after treatment, related to good response of motor and sensorial state. This is the first report of metabolic changes of brain in strabismus.
