ABSTRACT
Centralized care in dedicated centres, advances in antibiotic therapy, better nutritional support, and improved treatment of complications have resulted in a considerable improvement of health and life expectancy in both men and women with cystic brosis (CF).1-3 In 2011 the median survival of CF patients in the United States and Canada was 37 years. In observational cohort studies, early diagnosis of CF through
Introduction ..................................................................................................................1 Background ..................................................................................................................2
