ABSTRACT

PAOLA GAUFFIN CANO, ARLETTE SANTACRUZ, ÁNGELA MOYA, AND YOLANDA SANZ

5.1 INTRODUCTION

Obesity is considered a major health issue due to its increasing prevalence and associated co-morbidities (e.g. type 2 diabetes, fatty liver and cardiovascular disease) affecting both the developed and the developing world [1]–[2]. This disorder is the result of a long-term positive energy imbalance and is associated with a chronic state of low grade inflammation and immune dysfunction [3]–[5].