This chapter examines the privacy compliance challenges when dealing with  Big Data and provides guidance on how to comply with applicable privacy laws, regulations, and standards when implementing Big Data initiatives. Big Data is different from structured data in terms of the privacy issues and challenges in protecting personal data. There are two fundamental characteristics of Big Data that make it different: (1) The analysis of Big Data is often for a purpose different from the original purpose for which the data was gathered, and (2) the volume of data used for Big Data purposes can be vastly greater than that found in traditional structured databases.