ABSTRACT
ABSTRACT: Bacillus sp. produce a high number of secondary metabolites, some with antibiotic proprieties which can be used against biodeteriogenic filamentous fungi, source of serious damage in historic materials. These antagonistic proprieties are due to the production of bioactive lipopeptides which exhibit antifungal activity. The combined methodology of LC-ESI-MS and antifungal tests allowed the rapid identification of these bioactive compounds. This methodology constituted an efficient approach for the characterization of lipopeptides. The results show that Bacillus sp. CCMI 1051 produces different families of bioactive lipopeptides responsible for the inhibitory effect of biodeteriogenic fungal strains tested. These compounds can be used in the future as additives for production of novel biocides for conservation and restoration, constituting an efficient and environmental save solution for biodegradation/biodeterioration of our precious heritage.
