ABSTRACT

Wound healing and repair In earlier times the wound was assessed somewhat indirectly by studies of the breaking strength and collagen content. Today we look beyond these parameters to the behaviour of the individual cells in the wound since these are the prime movers in the healing process. Uneventful healing is dependent on their health and, in turn, this is determined by their microenvironment and a whole host of growth factors supplemented by growthpromoting and chemotactic substances produced primarily by platelets, lymphocyte cells and macrophages.