ABSTRACT
In the first edition of this book, three guidelines for management of recurrent pregnancy loss (RPL) were compared and contrasted, they were the protocol of the Royal College of Obstetricians (RCOG),1 the American College of Obstetricians and Gynecologists (ACOG)2 and the European Society of Human Reproduction and Embryology (ESHRE).3 The chapter in the first edition showed that each of the guidelines were different with widely differing recommendations. The RCOG guideline has been updated, with the latest edition published in 2011.4 The ESHRE protocol has not been updated, and the ACOG guideline was replaced by the American Society of Reproductive Medicine (ASRM) guideline in 2012.5 In addition, there are Dutch and Danish guidelines available. In the 7 years since the first edition of this book, it was hoped that the various guidelines would have developed a unified approach. Alas, this has not happened, and the guidelines are still very different in their approach to RPL.
