ABSTRACT
The interfaces between titanium alloy implants and the surrounding tissues play a critical role for the cells adhesion, proliferation, and differentiation as well as tissues ingrowth, and thus determining the good osteointegration. A biomimetic interface aims to mimic the biological environments of extracellular matrix (ECM) including surface chemistry and surface topography and thus benefits the friendly feeling by actin filopodia and consequently, final affinity recognition by several types of receptors in transmembrane protein, which directs the subsequent good reaction between cells/tissues and bone implants. This chapter summarised the recent progress of interfacial design of titanium alloy implants from the two aspects: surface structure and surface chemistry of implants by plasmabased techniques.
