ABSTRACT
In insects, the glutamate receptor template has extraordinarily wide usage. Not only are iGluRs involved in central synaptic transmission (Featherstone et al., 2005), they are also the receptor of the neuromuscular junction (Vesikansa et al., 2012). Further, a highly divergent family of about 60 subunits with the same domain architecture appear to be odorant receptors
(Benton et al., 2009). At least some of these genes can generate agonist-activated ion channels with similar pores to AMPA and KA receptors (Abuin et al., 2011). However, it is conceivable that some are not channels, given the signaling roles of delta, NMDA, and kainate subtypes distinct from ion transport (see Section 21.7).
