Using of the EPR Spin Labeling for the Investigation of the Synaptosomal Membrane Fluidity Changes Under Dimebon Injection in vivo

N. YU. GERASIMOV, O. V. NEVROVA, V. V. KASPAROV, A. L. KOVARSKIJ, A. N. GOLOSHCHAPOV, and E. B. BURLAKOVA

7.1 Aim and Background ..................................................................... 90 7.2 Introduction .................................................................................... 90 7.3 Experimental .................................................................................. 90 7.4 Result and Discussion .................................................................... 93 7.5 Conclusions .................................................................................... 98 Keywords ................................................................................................ 99 References ............................................................................................... 99

7.1 AIM AND BACKGROUND

Membrane structure plays important role in the development of dementia [6]. Therefore, it was important to investigate the membrane structural changes under neuroprotector injection.