ABSTRACT

The main goal of this work was the investigation of the actions of two types of synthetics biological active substances to the soluble proteins that enriched the animal’s blood serum. The first task was the test of the influence of plant growth regulator, applied in agriculture, Melafen, to the structural properties of soluble protein-bovine serum albumin (BSA). The second task was the investigation of the influence of hybrid antioxidants IHFANs that was expected to use as neuroprotectors, to the BSA structure properties

The first targets are the blood cells and the components of blood plasma also, when biological active substances appeared into the blood vascular system. This is why we carried out the serum albumin as the test for investigations of biological active substances actions. Serum albumins are water soluble globular proteins. Bovine serum albumin is a simple model of primary serum targets. The serum albumin has small size and, as the component that enriched blood plasma up to 50 percent, plays the essential role in the maintaining of osmotic balance sheets. As albumin enriches the blood sera, it facilitates the correct distribution of tissue liquid at many cases. The total area of all surfaces of albumins is biggest thanks to large amount of molecules and little molecular size of albumin. Besides this, the molecule may adsorb as hydrophilic, and the hydrophobe materials. These is why, the albumins are high effective carriers of most different molecules in blood plasma. And BSA takes essential part in transport of fatty acid, vitamins, hormones, and other materials that are needed to animal’s organism good functioning.