ABSTRACT
Interstitial lung disease is a common clinical entity. Approximately 22% of lung abnormalities seen in chest radiographs at the University of Chicago Medical Center are due to interstitial abnormalities. Interstitial disease is dened as an abnormality of the interstitial compartments of the lung, which may be due to inltration by inammatory or neoplastic cells or may be a consequence of the accumulation of uid or proteinaceous material (Genereux 1985). Despite of a common clinical entity, evaluation of interstitial lung diseases on chest radiographs and computed tomography (CT) images is
considered a dicult task for radiologists. is is partly because interstitial diseases create numerous radiographic patterns to which we refer as lung textures that are generally ill-dened and that include complex variations. erefore, if reliable quantitative measures of the lung textures related to interstitial diseases could be obtained from chest radiographs and CT images, it is likely that the accuracy and reproducibility in the evaluation of interstitial diseases could be improved.
