ABSTRACT

Chao Ma Guangdong Provincial Key Laboratory of Robotics and Intelligent System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, China

Jia Liu* & Pan-deng Zhang Guangdong Provincial Key Laboratory of Robotics and Intelligent System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China

Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, China

ABSTRACT: We proposed a new mathematical model to reconstruct the waveform of the Central Aortic Pressure (CAP) using continuous peripheral arterial blood pressure measured from the radial artery and finger artery separately. First, we formulated mathematical relations between Blood Pressure (BP) waveforms at the radial artery and finger artery. The radial blood flow waveforms are estimated via linear least-sequare and multichannel linear least-square deconvolution algorithm. Then combine with the measured radial BP waveforms to derive the CAP. To demonstrate the feasibility of this technique, we use three interventional surgery patients conducting human trials. The estimated CAP waveforms are very close to it’s measured (selected 10s segments, the RMSE is 2.74 mmHg). In conclusion, this new technology will be wider application in clinical trials and clinical practice.