ABSTRACT
This chapter presents classification & mode of action, indications & dermatological uses, formulations/presentation, dosages & suggested regimens, baseline investigations, considerations & monitoring, contraindications, cautions, important drug interactions, adverse effects & their management, use in special situations, and essential patient information of Mycophenolate Mofetil (MMF). MMF is a lymphocyte selective immunosuppressive agent. MMF thereby prevents the proliferation of T-cells, lymphocytes and the formation of antibodies by B-cells. MMF is used for the prophylaxis of acute organ transplant rejection and like several other immunosuppressive agents developed for this use, it has been found to be an effective treatment for various inflammatory dermatoses. MMF is licensed for use in combination with prednisolone or ciclosporin for the prevention of acute kidney, heart and liver transplant rejection. In patients who are unable to tolerate the gastrointestinal side-effects of MMF, mycophenolic acid delayed release tablets may be an alternative.
