Cognitive function is based on synaptic connections between neurons and neurons “synaptic” and information transmission. Neurons and information transmission between neurons are not immutable and frozen, but has great plasticity. While neuronal activity increases, the transmission of information between neurons and neurons capacity enhancement corresponding. Through the change of neuronal activity may alter cognitive ability. For example, glutamate is a neurotransmitter, it is to open the switch related to memory, and is conducive to the formation of memory. Ampakine, a class of chemical compounds, could enhance the activity of glutamate receptors, so as to enhance memory. The drug is developed with ampakine can be a cure for Alzheimer’s disease, also can make people more alert, but not addictive. Another compound, D-cycloserine, with a combination of certain glutamate receptors, can selectively enhance forget, thereby suppressing some of conditioned reflex reaction, such as anxiety, addiction and xenophobia, help to eliminate unpleasant memories. Modafinil can stay awake, and no neuroticism, nervous, mental collapse and other side effects produced by caffeine or amphetamine, as long as you can take one tablet, energetically working continuously for 40 hours and not sleepy. Ritalin (Methylphenidate) can improve the ADHD children’s learning performance, may also have a similar effect on normal children. A survey shows [3], the proportion of non medical use of cognitive enhancing drugs is as high as 20%, the Ritalin is the most commonly used cognitive enhancing drugs (about 62%), some cognitive enhancing drugs even can free online ordering. Therefore, cognitive enhancement, will become a kind of social phenomenon gradually.