ABSTRACT

The dried ripe fruits of Schisandra chinensis (Turcz.) Baill., are officially listed in the Chinese Pharmacopoeia as Wuweizi in Chinese and mainly used as a tonic and sedative. Schisandra contains lignans, polysaccharides, volatile oils, fatty acids, vitamins and amino acids etc. [1]. Schisandra lignans is one of the most important ingredients with pharmacological activities [2]. Lignin was the main composition of Schisandra chinensis oil, had hypoglycemic effects on type 1 diabetes mellitus rats induced by alloxan, but the mechanism is unclear[3]. Therefore, it could provide theoretical basis for the development of hypoglycemic drugs by understanding the hypoglycemic effect and mechanism of Schisandrae chinensis lignin.