ABSTRACT

Classic histoplasmosis or histoplasmosis capsulati is a systemic endemic mycosis, caused by the thermally dimorphic fungus Histoplasma capsulatum var. capsulatum. This microorganism lives in the environment, especially in the soil, where it exists as mould. In blood-agar medium at 37ºC and in tissues it grows as a budding yeast. In the infected organs these yeasts are inside the cells of the reticuloendothelial system (Arenas 2011; Bonifaz 2012).