ABSTRACT
Hyaluronan (HA) is a high-molecular weight, naturally occurring linear polysaccharide and found in all tissues and body fluids of higher animals. The excellent properties of HA such as biodegradability, biocompatibility, safety, excellent mucoadhesive capacity and high water retaining ability make it well-qualified for using in various bio-medical applications. In addition; HA is nontoxic, noninflammatory and nonimmunogenic. Because of all these advantages, HA has received much attention as a matrix for drug delivery system. This review will summarize our present knowledge about HA, properties and its development in some pharmaceutical applications.
