ABSTRACT

Conventional X-rays have been used in diagnostic imaging since the X-ray was discovered by Roentgen in 1895. In X-ray imaging contrast is generated by the dierent X-ray attenuation in the object due to its varying composition, thickness or density. For biological tissues containing muscle and bones a sharp image is obtained by conventional X-ray imaging due to the dierence in X-ray attenuation between the muscle and the bone. However, soft tissue contrast is limited in X-ray imaging because there are only slight dierences in the attenuation of these regions. In contrast, X-ray phase contrast imaging (X-PCI) is a major conceptual and practical advance in the use of X-ray imaging that is based on the phase change eect on the X-ray intensity image[1].