ABSTRACT
MC-CE Devices ................................................................................ 10 1.3.2 Fabrication of MC-CE Devices by CO2 Laser Ablation
on PMMA .......................................................................................... 10 1.4 Integration of MC-CE Devices for Sample Preparation and
Analyte Detection ........................................................................................ 13 1.4.1 Integrating MC-CE Devices for Sample Preparation .................. 14 1.4.2 Integrating MC-CE Devices to Enhance Detection Sensitivity
and Selectivity for Analyte Detection ................................................16 1.4.2.1 ECD/Dual-Electrode Detection ...................................... 16 1.4.2.2 QD-Assisted Detection ..................................................... 18
1.5 Application of MC-CE Devices .................................................................. 18 1.6 Aim and Outline of This Book ................................................................... 20 References ............................................................................................................... 21
Due to the rising demand for on-site analysis to deliver timely results in the diagnosis of infective agents and treatment of patients under critical conditions, assay of drugs and metabolites at point-of-care, on-site toxic agent detection for home security, and monitoring of environmental pollutants and food contaminants, various methods capable of on-site operation have been developed in the past 20 years. There are two major methods adopted in various analytical methodologies: direct methods, via specic biochemical reactions with target analytes normally present at high levels in a simple sample matrix; and separation methods, via a separation scheme to separate analytes normally present at low levels in complex samples containing interfering substances [1-3].
